Toxic Chemicals, Toxicity Testing: Consensus Reports

The division produces 60-70 reports per year. These reports are unique, authoritative expert evaluations. Each report is produced by a committee of experts selected by the Academy to address a particular statement of task and is subject to a rigorous, independent peer review. The experts who volunteer their time participating on study committees are vetted to make sure that the committee has the range of expertise needed to address the task, that they have a balance of perspectives, and to identify and eliminate members with conflicts of interest. All reports undergo a rigorous, independent peer review to assure that the statement of task has been addressed, that conclusions are adequately supported, and that all important issues raised by the reviewers are addressed. Thus, while the reports represent views of the committee, they also are endorsed by the Academy.

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Showing results 1 - 5 of 68

Monitoring and Sampling Approaches to Assess Underground Coal Mine Dust Exposures (2018)

Coal mine dust lung disease continues to be an important and complex problem affecting coal miners in the United States. Although the number of cases dropped precipitously since the late 1960s, an increase in the prevalence and severity of the disease has been documented since about 2000. Reliable information on respirable coal mine dust (RCMD) exposures in underground coal mines is crucial for predicting, reducing, and preventing mine workers... More >>

Report in Brief

Review of Report and Approach to Evaluating Long-Term Health Effects in Army Test Subjects: Final Report (2018)

Between 1942 and 1975, the U.S. Army conducted tests with human subjects to study the effects of a variety of agents, including chemical warfare and biological agents. A recent report evaluated the potential long-term health effects in these former test subjects from their exposures. The report was prepared to assist the Army with making determinations regarding medical care for the test participants. A two-part study by the National Academie... More >>

Review of Report and Approach to Evaluating Long-Term Health Effect in Army Test Subjects -- Interim Report (2018)

Between 1942 and 1975, the U.S. Army conducted tests with human subjects to study the effects of a variety of agents, including chemical warfare and biological agents. A recent report evaluated the potential long-term health effects in these former test subjects from their exposures. The report was prepared to assist the Army with making legal determinations regarding medical care for the test participants. This two-phase study examines whethe... More >>

Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals (2017)

The U.S. Environmental Protection Agency (EPA) regulates toxic chemicals as part of its mission to protect human health and the environment. Traditional toxicity testing relies heavily on studies that expose test animals to chemicals at amounts much higher than typical human exposures (i.e., low doses). However, some chemicals can cause health effects at low doses. This report outlines a strategy to improve EPA's ability to evaluate evidence o... More >>

Report in Brief

Using 21st Century Science to Improve Risk-Related Evaluations (2017)

The availability of tools to assess human health risks from chemical exposures have increased rapidly in the 21st century. For example, new personal sensors and sampling techniques offer unparalleled opportunities to characterize individual exposures, new in vitro assays can now evaluate a number of cellular processes and responses, and -omics technologies have advanced molecular epidemiology, which focuses on underlying biology rather tha... More >>

Report in Brief